Diagnostic Imaging Modalities for Skeletal Metastasis in Soft Tissue Sarcoma

Soft tissue sarcomas (STS) are usually highly malignant. Bone metastasis is less common in STS but it significantly affects patients` quality of life and also is indicator of poor prognosis. Different types of imaging modalities are available for diagnosis and follow-up of STS. Bone scintigraphy is a sensitive and cost effective method for screening bone metastases however it`s poor specificity must be covered by other imaging methods like computed tomography. More sophisticated methods are available including whole body magnetic resonance imaging (MRI) and positron emission tomography (PET). Equipment limitations and high costs are the main problems with ofthese methods.